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Stars stand for the overview position, or the extent of assessment supporting the submitted (SCV) record. This price is calculated by NCBI based on knowledge in the submitter.

The number of variants in ClinVar for this gene, like more compact variants in the gene and larger CNVs that overlap or totally incorporate the gene.

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This date signifies the final time this VCV document was current. The update may very well be on account of an update to one of the incorporated submitted documents (SCVs), or as a result of an update that ClinVar designed towards the variant for instance adding HGVS expressions or possibly a rs range.

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The aggregate germline classification for this variant, commonly for any monogenic or Mendelian disorder as from the ACMG/AMP suggestions, or for reaction to some drug. This price is calculated by NCBI depending on details from submitters. Go through our rules for calculating the mixture classification.

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